For Dermatologic Use Only ➺ Ammonium lactate cream is available in 280 grams (two 140 gram… Use twice daily or as directed by a physician. Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Get free shipping at $35 and view promotions and reviews for Amlactin Daily Moisturizing Body Lotion 12% The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. I've been using it for years, including back when it was only available by prescription here. There are, however, no adequate and well-controlled studies in pregnant women. The mutagenic potential of ammonium lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. In dermal Segment I and III studies with Ammonium Lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Use twice daily or as directed by a physician. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. It is a moisturizer that is designed to treat the symptoms of dry, scaly skin conditions such as ichthyosis vulgaris and xerosis. Caution is advised when used on the face because of the potential for irritation. This is a serious creme that provides incredible relief and promotes healing, but it is not a quick-absorb lotion so one will need gloves to help with absorption. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. Use exactly as directed on the label, or as prescribed by your doctor. There are, however, no adequate and well-controlled studies in pregnant women. Ammonium lactate is an anti- itch topical medication formulated from 12% lactic acid and ammonium hydroxide. Shake the lotion form of this medication well just before using it. Ammonium lactate hydrates the outermost skin layer and promotes skin moisturizing for a prolonged time. This medicine is a white, lotion ‹ Back to Gallery. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. Shake well. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. For lot number and expiration date, see bottle. Lac-Hydrin specially formulates 12% lactic acid, neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.4-5.5. Apply to the affected areas and rub in thoroughly. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. For lot number and expiration date, see bottle. Use twice daily or as directed by a physician. I think soaking is … Many lotions and creams sting terribly and cause worse suffering, but Ammonium Lactate cream is so cooling and soothing and does not further irritate my sensitive skin. But the smell dissipates, and for many, it truly helps heal dry skin. Shake well. CONTAINS: *Ammonium lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Ammonium Lactate Cream, 12% also contains cetyl alcohol, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. color white shape No data. CONTAINS: *Ammonium Lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Select one or more newsletters to continue. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. and Milwaukee, Wisconsin A double-blind, paired comparison study was used to evaluate treatment effects of 12% ammonium lactate lotion (Lac-Hydrin) against its … Keep your skin looking smooth, vibrant and healthy with this Ammonium Lactate 12 Percent Cream. Not for Ophthalmic, Oral or Intravaginal Use. For external use only. ➺ It is available in the form of cream as well as lotion. Because many drugs are excreted in human milk, caution should be exercised when Ammonium Lactate is administered to a nursing woman. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. Any ammonium lactate lotion will have this smell - I have used several brands with success. The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% ammonium lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. No unusual toxic effects were reported. imprint No data. Evaluation of ammonium lactate in the treatment of seborrheic keratoses Maria V. Klaus, MD,a Richard F. Wehr, BS,b Roy S. Rogers III, MD,c Thomas J. Russell, MD: and Lincoln Krochmal, MOb Buffalo, New York, Rochester, Minnesota. In general, dose selection for an elderly patient should be cautious. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. Ammonium lactate is usually applied twice a day. Ammonium lactate also prevents keratinization of epidermal skin layer, which keeps skin smoother and hydrated for a longer time. * by AmLactin Ammonium Lactate; Third Edition Ammonium Lactate Lotion 12%C-P , Fliptop - (400grams/14oz) - Pack of 2; Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube by Major Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Because many drugs are excreted in human milk, caution should be exercised when ammonium lactate is administered to a nursing woman. Do not use in larger or smaller amounts or for longer than recommended. * by AmLactin Ammonium Lactate… The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. Not for Ophthalmic, Oral or Intravaginal Use. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Medically reviewed by Drugs.com. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. The oral administration of Ammonium Lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). Last updated on Sep 21, 2020. However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% Ammonium Lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. ammonium lactate 12 % topical cream. Perrigo New York Inc, For Dermatologic Use Only The alpha-hydroxy acids (and their salts) may act as … Not for Ophthalmic, Oral or Intravaginal Use, We comply with the HONcode standard for trustworthy health information -, Lactic Acid and Ammonium Hydroxide Lotion. Apply to the affected areas and rub in thoroughly. An in vitro study of percutaneous absorption of Ammonium Lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. Clinical studies of ammonium lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. It is usually applied to the affected skin area twice daily. Rash and peeling skin may also occur. For external use only. Caution is advised when used on the face because of the potential for irritation. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% ammonium lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Apply ammonium lactate at around the same time (s) every day. Other reported clinical experience has not identified differences in responses between elderly and younger patients. This property may influence hydration of the stratum corneum. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. Lotions are thinner and lighter in consistency and can be used all over the body (for example, in case of eczema). Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. … Lactic acid is an alpha-hydroxy acid. August 22, 2012 at 2:36 pm Ammonium lactate is commonly sold over the counter by the name of amlactin, LAC lotion, or LAC hydrin. The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. ammonium lactate 12 % lotion. Less frequently occurring side effects include irritation, dryness, eczema, changes in skin color, or small … *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.5 - 5.5. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to Ammonium Lactate formulations. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as Ammonium Lactate to provide a lotion pH of 4.5 - 5.5. No unusual toxic effects were reported. hydroxyzine, hydrocortisone topical, lidocaine topical, diphenhydramine, Benadryl, Eucerin, Aquaphor, AmLactin, dimethicone topical, CeraVe. The oral administration of ammonium lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). Usual Dosage: Shake well. Apply to the affected areas and rub in thoroughly. The mechanism(s) by which this is accomplished is not yet known. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Available for Android and iOS devices. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. This topical medication is made from 12% lactic acid and ammonium hydroxide. Distributed By Perrigo, Allegan, MI 49010. The mutagenic potential of Ammonium Lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. Sadly, a small percentage of you may experience a negative reaction to the lotion. Ammonium lactate comes as a cream and a lotion to apply to the skin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Set id: dc3a6462-0f2c-4306-b5ef-c7b47395e959, Not for Ophthalmic, Oral or Intravaginal Use, 225 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product, 400 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. The mechanism(s) by which this is accomplished is not yet known. This property may influence hydration of the stratum corneum. The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). In general, dose selection for an elderly patient should be cautious. Distributed By Perrigo, Allegan, MI 49010. Use twice daily or as directed by a physician. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It is a normal constituent of tissues and blood. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to ammonium lactate formulations. Usual Dosage: Shake well. Safety and effectiveness of ammonium lactate have been demonstrated in infants and children. Apply to the affected areas and rub in thoroughly. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. I use it on hands, feet, knees. Safety and effectiveness of Ammonium Lactate have been demonstrated in infants and children. AMMONIUM LACTATE- ammonium lactate lotion Clinical studies of Ammonium Lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. In dermal Segment I and III studies with ammonium lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% Ammonium Lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Other reported clinical experience has not identified differences in responses between elderly and younger patients. This Ammonium Lactate cream infuses skin with moisture and smooths it out to give it a younger and healthier appearance. The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. ➺ Common brand names: Lac-Hydrin, AmLactin, Geri-Hydrolac, LAClotion, LAC Cream, Al-12 ➺ Generic name: ammonium lactate ➺ Drug class and mechanism: It is an anti-itch prescription medicine. I have been given Lac Hydrin over the years but I hate it because it stings badly if any of your skin is irritated or cracked. An in vitro study of percutaneous absorption of ammonium lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). The most frequent side effect of using topical 12 percent ammonium lactate lotion is a stinging or burning sensation. Amlactin Daily Moisturizing Body Lotion 12% at Walgreens. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Medicine is a normal constituent of tissues and blood of the label, or as directed by physician... Not identified differences in responses between elderly and younger patients lot number and expiration date see. Directions on your prescription label carefully, and hyperpigmentation Body ( for example, case. Of the stratum corneum only available by prescription here there are, however, adequate. 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